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In the 1970s, clinical trials on patients with terminal cancer showed that intravenous high-dose ascorbate treatment, that achieved a peak plasma concentration of 6 mM, extended their survival (143, 144), whereas in the 1980s they failed to confirm these findings because ascorbate was given at the same dose orally and the peak plasma concentration was of less than 200 M (145, 146)
The combination exists in clinical practice based on pharmacological reasoning and extrapolation from related studies, not direct evidence
Compounded preparations are dispensed by a licensed 503A pharmacy pursuant to a prescription based on documented clinical need
It must involve either an action of an inhibitory neurotransmitter or reduction of a stimulatory one
Most of our clients goals are achieved between 3 months and 1 year
